Search results for "pathology [Aging]"

showing 10 items of 1700 documents

Aufgaben und Einsatz eines Rechtsmedizinischen Institutes in katastrophen�hnlichen F�llen

1975

Katastrophen und katastrophenahnliche Massenunfalle treten ohne Ankundigung plotzlich ein. Statistisch gesehen sind diese Ereignisse erfreulich selten. Vorsorgeorganisation fur den Ernstfall sollte dennoch jedes Rechtsmedizinische Institut treffen. Empfehlenswert sind Wandtafeln, die eine sog. Institutsmobilmachung erleichtern. Bildung von Sektionsteams und Vorgehen nach einem Phasenplan sind hilfreich.

AnatomyPathology and Forensic MedicineZeitschrift f�r Rechtsmedizin
researchProduct

Mast Cells and Th17 Cells Contribute to the Lymphoma-Associated Pro-Inflammatory Microenvironment of Angioimmunoblastic T-Cell Lymphoma

2010

Reports focusing on the immunological microenvironment of peripheral T-cell lymphomas (PTCL) are rare. Here we studied the reciprocal contribution of regulatory (Treg) and interleukin-17-producing (Th17) T-cells to the composition of the lymphoma-associated microenvironment of angioimmunoblastic T-cell lymphoma (AITL) and PTCL not otherwise specified on tissue microarrays from 30 PTCLs not otherwise specified and 37 AITLs. We found that Th17 but not Treg cells were differently represented in the two lymphomas and correlated with the amount of mast cells (MCs) and granulocytes, which preferentially occurred in the cellular milieu of AITL cases. We observed that MCs directly synthesized inter…

Angioimmunoblastic T-cell lymphomaLymphomaInflammationBiologymedicine.disease_causeCXCR3Lymphoma T-CellCXCR5Pathology and Forensic MedicineAutoimmunityAnimals Chemokine CXCL13; immunology Cytokines; genetics/immu/nology Forkhead Transcription Factors; immunology Gene Expression Profiling Humans Immunoblastic Lymphadenopathy; immunology/pathology Inflammation; immunology Interleukin-17; immunology Interleukin-6; immunology Lymphoma; T-Cell; immunology/pathology Mast Cells; immunology Microarray Analysis Th17 Cells; immunology Tumor MicroenvironmentimmunologymedicineTumor MicroenvironmentAnimalsHumansMast CellsInflammationTumor microenvironmentInterleukin-6Gene Expression ProfilingInterleukin-17Forkhead Transcription FactorsMast cellmedicine.diseaseT-CellMicroarray AnalysisChemokine CXCL13humanitiesgenetics/immu/nologyLymphomamedicine.anatomical_structureImmunoblastic LymphadenopathyImmunologyCytokinesimmunology/pathologyTh17 CellsMast Cell microenvironment angioimmunoblasticmedicine.symptomRegular Articles
researchProduct

The relationship between animal cruelty in children and adolescent and interpersonal violence: A systematic review

2019

Abstract The following study is a systematic review of the relationship between animal cruelty and interpersonal violence. The systematic literature review following PRISMA guidelines and combined with the application of inclusion and exclusion criteria, enabled us to locate 32 studies published between 1995 and July 2017. Overall, the results show that episodes of animal cruelty during childhood and adolescence tend to co-occur alongside other forms of violent and antisocial behaviors. Cruelty to animals was associated with bullying, behavioral problems, experiences of abuse (emotional, physical and sexual), and juvenile delinquency. Furthermore, recurrent animal cruelty during childhood a…

Animal abuse2734Poison controlCrueltyInterpersonal violencePathology and Forensic MedicineDevelopmental psychologyInjury preventionJuvenile delinquencyHuman violenceCruelty to animals0501 psychology and cognitive sciencesAntisocial behaviorAnimal cruelty050901 criminology05 social sciencesHuman factors and ergonomicsChildhoodAdolescenceClinical PsychologySystematic reviewPsychiatry and Mental HealthAdolescence; Animal abuse; Animal cruelty; Antisocial behavior; Childhood; Human violence; Interpersonal violence; Systematic review; 2734; Clinical Psychology; Psychiatry and Mental HealthSystematic review0509 other social sciencesPsychologyDeviance (sociology)050104 developmental & child psychology
researchProduct

The venous system in health and disease. AMN Gardner and RH Fox (eds). IOS Press, The Netherlands, 2001. No. of pages: 306. ISBN: 90 5199 433 8

2002

AnthropologyEnvironmental ethicsDiseaseSociologyPathology and Forensic MedicineThe Journal of Pathology
researchProduct

Intramembrane particles and filipin labelling on the membranes of autophagic vacuoles and lysosomes in mouse liver

1989

Morphologically detectable protein (intramembrane particles) and cholesterol (filipin labelling) in the membranes of autophagic vacuoles and lysosomes were studied in mouse hepatocytes using thin-section and freeze-fracture electron microscopy. Both isolated autophagic vacuoles and lysosomes, and intact tissue blocks were used due to the facts (i) that lysosomes are difficult to recognize in freeze-fracture replicas of intact hepatocytes, and (i) that filipin penetration into the tissue blocks is unsatisfactory. Intramembrane particle density was low in the membranes of early autophagic vacuoles (defined as round-shaped vacuoles in which an inner membrane parallel with the outer limiting me…

Antifungal AgentsHistologyVacuoleBiologyFilipinPathology and Forensic MedicineMice03 medical and health scienceschemistry.chemical_compoundPhagocytosisLysosomeOrganelleAutophagymedicineAnimalsFreeze FracturingFilipin030304 developmental biologyPhagosome0303 health sciencesVesicle030302 biochemistry & molecular biologyBiological membraneCell BiologyCell biologymedicine.anatomical_structureMembraneLiverchemistryVacuolesLysosomesCell and Tissue Research
researchProduct

Progress in electron microscopic diagnostics: semi-quantitative determination of precipitable calcium in different cell types of the organ of Corti i…

1991

Potassium antimonate was used to precipitate calcium in the cochlea of the guinea-pig. The distribution of the calcium antimonate precipitates was analysed by electron microscopy. The precipitate density was determined in different cell types in the organ of Corti by counting the number of calcium binding sites in a 10-micron 2 area. The size of the precipitates varied considerably, and thus the relative amount of the precipitable calcium was estimated only semi-quantitatively. As the prominent carbon signal is superimposed over the nearby small Ca(2+)-edge signals, the combined signal of the antimony M4,5-edge and the oxygen K-edge of the calcium antimonate salt formed was chosen for the s…

AntimonyCytoplasmHistologyGuinea PigsAnalytical chemistrychemistry.chemical_elementCalciumPathology and Forensic Medicinelaw.inventionAntimonylawHair Cells AuditoryMicroscopyImage Processing Computer-AssistedmedicineAnimalsChemical PrecipitationOrgan of CortiCochleaOrganellesPrecipitation (chemistry)Spectrum AnalysisMitochondriaMicroscopy Electronmedicine.anatomical_structurechemistryOrgan of CortiCytoplasmCalciumElectron microscopeJournal of Microscopy
researchProduct

Melatonin protects against ischemia-reperfusion injury and inhibits apoptosis in isolated working rat heart.

2003

INTRODUCTION: Melatonin (MEL), a pineal hormone, is well known as a potent antioxidant in a variety of ischemia-reperfusion models. Recent studies have assumed a pivotal role of reactive oxygen species (ROS) in the development of apoptosis. There are few pieces of information concerning a possible protective role of MEL against apoptosis in ischemia-reperfusion injury of myocardium. METHODS: We conducted an in vitro experiment: (1) to study the effect of MEL in the model of isolated and perfused working rat heart; (2) to evaluate the antioxidant capacity of MEL by a simple fluorescence test; and (3) to analyze the extent of apoptosis inhibition by MEL. Four groups of male Wistar rat were us…

Antioxidantmedicine.medical_treatmentIschemiaPharmacologymedicine.disease_causePathology and Forensic MedicineMelatonin03 medical and health sciences0302 clinical medicinehemic and lymphatic diseasesPhysiology (medical)medicineneoplasms030304 developmental biologychemistry.chemical_classification0303 health sciencesReactive oxygen speciesTUNEL assaymedicine.disease3. Good healthchemistryApoptosisAnesthesiaReperfusion injury030217 neurology & neurosurgeryOxidative stressmedicine.drugPathophysiology : the official journal of the International Society for Pathophysiology
researchProduct

Early results of a low-profile stent-graft for thoracic endovascular aortic repair

2020

Purpose To assess outcomes of a low-profile thoracic stent-graft in the treatment of thoracic aortic pathologies. Methods A retrospective analysis of all consecutive patients with aortic thoracic pathologies treated with the RelayPro device in two university hospitals between October 2018 and July 2019. Results 23 patients (65% men; mean age 63.4 ± 15 years) were treated. Pathologies included aortic dissections (n = 10), 5 residual type A (22%) and 5 type B (22%), 6 degenerative aortic aneurysms (26%), 4 penetrating aortic ulcers (17%), and aortic erosion, intramural hematoma and aortic rupture (n = 1 and 4% in each case). Two cases (9%) were emergent and two urgent. Proximal landing was a…

Aortic archElephant trunksEndoleakCardiovascular ProceduresPhysiologymedicine.medical_treatmentVascular SurgeryAorta ThoracicPathology and Laboratory MedicineNervous SystemPostoperative ComplicationsMedicine and Health SciencesLeukocytosisAortaCerebrospinal FluidAged 80 and overMultidisciplinaryQRArteriesMiddle AgedBody FluidsTreatment OutcomeMedicineEngineering and TechnologyFemaleStentsmedicine.symptomAnatomyResearch ArticleBiotechnologymedicine.medical_specialtyScienceAortic DiseasesBioengineeringSurgical and Invasive Medical ProceduresBlood Vessel Prosthesis Implantationmedicine.arterymedicineHumansAortic ruptureAgedRetrospective StudiesAortabusiness.industryStentBiology and Life SciencesVascular surgerySurgeryAppositionSurgical RepairAnatomical PathologyCardiovascular AnatomyBlood VesselsMedical Devices and EquipmentbusinessPLoS ONE
researchProduct

On Pathways for Small Molecules Into and Out of Human Hair Fibers

1996

This paper represents an experimental approach of histology of the human hair fiber in dyeing and diffusion phenomena and its contribution to the interpretation of hair analysis results for drug abuse. Rhodamine B was applied to human hair fibers from either aqueous solution or methanol/ethanol solvent. The experiments were performed on natural hair of different ethnic groups as well as on extensively bleached hair strands. The microscopical study of the pathway of diffusion of rhodamine B into the hair fibers indicated that the reagent had entered the unmodified fibers at the scale edges between the cuticle cells. At the beginning of the diffusion process intercellular diffusion was the pr…

Aqueous solutionHair analysisAnalytical chemistryPenetration (firestop)Pathology and Forensic MedicineSolventchemistry.chemical_compoundchemistryReagentGeneticsRhodamine BBiophysicsMethanolDyeingJournal of Forensic Sciences
researchProduct

Arachnid oenocytes: ecdysone synthesis in the legs of harvestmen (Opilionidae).

1981

Cells measuring up to 130 microns have been found in the proximal segments of the femora of all four pairs of walking legs in various species of harvestmen (Phalangium opilio, Leiobonum limbatum, Opilio parietinus, and Opilio ravennae). These cells exhibit all the fine-structural characteristics of insect oenocytes, in particular the conspicuous agranular endoplasmic reticulum. Radioimmunoassay after in vitro incubation of these cells has demonstrated the synthesis of alpha- and beta-ecdysone. These ecdysteroids have been found in the ovaries and tergites of the opisthosoma as well as in the oenocytes.

ArachnidEcdysoneHistologybiologyOpilio parietinusOpisthosomamedia_common.quotation_subjectSpidersCell BiologyAnatomyInsectIn vitro incubationbiology.organism_classificationEndoplasmic ReticulumPhalangium opilioPathology and Forensic MedicineAnimalsFemurOpilioEcdysone synthesismedia_commonCell and tissue research
researchProduct